Cabrela House / Orgânica Arquitectura

first_img Portugal Cabrela House / Orgânica ArquitecturaSave this projectSaveCabrela House / Orgânica Arquitectura CopyHouses•Sintra, Portugal ShareFacebookTwitterPinterestWhatsappMailOr Clipboard Cabrela House / Orgânica Arquitectura “COPY” ShareFacebookTwitterPinterestWhatsappMailOr Clipboard Photographs:  Fernando Guerra | FG+SGText description provided by the architects. On the site we found ruins of a house waiting to be recovered. We preserved the limit walls and we designed an exterior space, allowing the new house to emerge from the old. Save this picture!ElevationAt the same time we harmonized the smalls existing volumes that follow the house next door. The main floor houses the kitchen, the living room and a small studio, while the first floor is a more private area with two bedrooms. Save this picture!© Fernando Guerra | FG+SGProject gallerySee allShow lessNew Taipei City Museum of Art Competition Proposal / INFLUX_STUDIOArticlesPower in Space ConferenceArticles Share Projectscenter_img Architects: Orgânica Arquitectura Area Area of this architecture project Save this picture!© Fernando Guerra | FG+SG+ 14 Share Area:  142 m² Photographs Houses ArchDaily “COPY” CopyAbout this officeOrgânica ArquitecturaOfficeFollowProductsSteelStoneConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesSintraHousesPortugalPublished on August 24, 2011Cite: “Cabrela House / Orgânica Arquitectura” 24 Aug 2011. ArchDaily. Accessed 12 Jun 2021. ISSN 0719-8884Read commentsBrowse the CatalogAluminium CompositesTechnowoodWood Siding in KSR Villa BodrumWindowsMitrexSolar WindowMetal PanelsAurubisCopper Alloy: Nordic RoyalVentilated / Double Skin FacadeSTAC BONDAssembly Systems – GluedLightsLouis PoulsenLamps – LP Slim BoxUrban ApplicationsIsland Exterior FabricatorsPublic Safety Answering Center II Envelope SystemPodsTrimoModular Space SolutionsHanging LampsAxolightPendant Lights – HoopsStonesFranken-SchotterFlooring and Wall Tiles – Dietfurt LimestoneVentilated / Double Skin FacadeULMA Architectural SolutionsPaper Facade Panel in Nokia LibraryCabinetsburgbadWall Cabinet – Sys30AcousticUnika VaevAcoustics – Ecoustic® Foliar TileMore products »Read commentsSave世界上最受欢迎的建筑网站现已推出你的母语版本!想浏览ArchDaily中国吗?是否翻译成中文现有为你所在地区特制的网站?想浏览ArchDaily中国吗?Take me there »✖You’ve started following your first account!Did you know?You’ll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my streamlast_img read more

Business commons to begin construction in May 2016

first_imgJessica Ranck Jessica Ranck Gender gap increases in colleges around the nation ReddIt printThe Neeley School of Business is planning for its next major renovation.Last year, Spencer and Marlene Hays donated $30 million to help build a new business commons for TCU students.Since then, the school’s dean, along with a committee of Neeley employees and Canon Design, has been working to create blueprints for the new and renovated buildings in the business commons, the director of marketing and communications for the Neeley School of Business Jeffrey Waite said.The two-year project is expected to begin construction in May 2016.The construction plan adds two new buildings and remodels Tandy Hall, Dan Rogers Hall and Steve & Sarah Smith Entrepreneurs Hall.The new space is expected to change the way the business school approaches learning and engagement, said O. Homer Erekson, the John V. Roach Dean of the Neeley School and professor of managerial economics and strategy.Erekson said the broad idea is that the whole school is connected so students can essentially move from one building to the next.编辑触摸共享全屏制作你自己的了解更多接触图片分享图像…全屏The new buildings will have more space for students to work on group projects, study and hang out with friends.Many professors in the Neeley School said they think the addition of those spaces will help students get a better idea of what the business world will be like.“Once outside the confines of TCU, students will have to interact with colleagues in a variety of settings,” marketing professor Vanessa Shropshire said. “The more chance[s] we give students to intermingle with each other, the better.”Tandy Hall and Dan Rogers Hall will be considered the “core academic building,” Erekson said.The second floor of the connected buildings will be designated for classrooms, while the third floor will be for faculty offices.Many of Neeley’s professors said they think it will be beneficial to have all the staff located in one area.“I love collaborating with other professors and [having faculty offices located near each other] will make it much easier,” Shropshire said.Dan Rogers will also be home to career services and academic advising. It will include a dining option on the first floor to meet the needs of hungry students.Smith Hall will be renovated as part of the last phase of the construction process.The hall will still promote entrepreneurship, but its amenities will be changed to reflect the atmosphere of a working environment.The first floor of Smith will be changed from a place where students relax between classes to an area where they can work, talk with employers or even start up their own student companies, Erekson said.Erekson said Neeley’s goal with the business commons is to make it a place to learn both inside and outside the classroom.Senior marketing major Carly Hirvela said she thinks the new buildings will give students a glimpse of what it’s like to work in their specific field of study before graduating.“I think the atmosphere will help the students learn more about the environments that they will be entering,” Hirvela said.The new building located behind Dan Rogers is yet to be named, but will include additional classroom space for students.Many business students said they are most excited for the outdoor seating that will be located in the middle of the commons because they feel that type of space is currently lacking.“In between classes, there’s really no place to hang out, unless you want to hang out inside Smith, which is kind of crowded,” senior finance major Perry Locke said. “So I think it will be nice to have some place outside with a little more relaxing feel where everyone can congregate.”How administration will accomodate classes and faculty offices during the construction period is still in the planning stages, Waite said.“We will look for classroom space outside of Neeley,” Waite said. “Faculty and staff offices may occupy portable buildings during the construction phase.”The business commons is expected to cost about $100 million, senior finance major and Neeley ambassador Sarah Doherty said.Erekson said the school is still looking for donors to help fund the project and construction may be delayed if sufficient funds are not in order. Linkedin Facebook The College of Science and Engineering Dean, Phil Hartman, retires after 40 consecutive years Jessica Ranck is a junior journalism major from San Diego, California. She currently serves as the Greeks/SGA/SDS editor for TCU 360. Jessica Ranck Closures continue on I-35 Students hang out and study outside Smith Hall before class. Linkedin McLeland Tennis Center kicks off celebration with a serve Facebook Previous articleChristmas comes early in CowtownNext articleSpeaker: ‘Superhuman things’ happening in Rwanda Jessica Ranck RELATED ARTICLESMORE FROM AUTHOR Students debut performances of drag personas as part of unique new course + posts Twitter Jessica Ranck ReddIt Jessica Ranck Twitter Political involvement remains low among TCU students Condensed semester, lost week to snowstorm adding to some students stress during finals weeklast_img read more

Call for special hearings after upsurge in numbers of journalists facing court

first_img New Cyber Crimes Law restricts free expression and targets online activists July 2, 2008 – Updated on January 20, 2016 Call for special hearings after upsurge in numbers of journalists facing court KuwaitMiddle East – North Africa Follow the news on Kuwait Receive email alerts Help by sharing this information February 23, 2015 Find out more Reporters Without Borders expressed its disquiet at an upsurge in cases being brought against journalists in Kuwait, despite the fact it was the first Gulf state to decriminalise press offences.“The 2006 press law reform profoundly transformed the emirate’s media landscape. We urge the authorities to continue to strengthen the protection of the right to be informed and to inform the public”, the worldwide press freedom organisation said.“The appointment of special judges at a time of a rising number of disputes, would provide an extra guarantee to journalist defendants”, the organisation added.Fuad al-Hashem, of Kuwaiti daily al-Watan was on 28 May 2008 ordered to pay the equivalent of almost 22,000 euros in damages for defamation as a result of three cases brought by the Prime Minister of Qatar, Sheikh Hamad ben Jassem al-Thani. He had accused the journalist of harming his reputation in his articles dealing with his relations with the state of Israel. Al-Hashem told Reporters Without Borders that he has faced more than 20 proceedings against him, most of them brought by deputies, who accused him of damaging their image with their electorate.“These days Kuwaiti journalists have to take great care and avoid resorting to self-censorship to protect themselves from the intolerance of some politicians who do not accept any criticism”, he said. His appeal has been set for September 2008.In another case, Saad al-Ajimi, correspondent for satellite news channel al-Arabiya, is being sued for “insult” following a defamation case brought by religious leader Hamid al-Ali. The journalist was interviewed by the prosecutor’s office on 8 June 2008, more than five months after the broadcast, on 1st February, of the programme Sina’at al-Mowt (the death industry) about “the history of al-Qaeda in Kuwait”. In reference to the complainant, the journalist had said that members of the movement had met “several religious fundamentalist dignitaries in Kuwait”.Al-Ajimi told Reporters Without Borders that “the number of cases laid against journalists in Kuwait has risen constantly since reform of the press law, which certainly removed the threat of imprisonment for journalists but provided for fines which are far too harsh.”Faisal al-Qinai, Secretary General of the Kuwaiti Journalists’ Association told Reporters Without Borders that scores of journalists had asked for legal assistance to defend themselves at these trials. Such was the case of Ahmed Abderrahman al-Quss, who also works for the daily al-Watan and is facing a defamation case brought by the deputy Ali al-Rashid, who is seeking 100,000 dinars (238,000 euros) in damages. The Kuwait parliament in March 2006 adopted a new press law allowing far greater freedom to the emirates’ journalists. The decriminalisation of press offences however remains limited, since the new law contains numerous exceptions – such as damage to religion – that come under the criminal code. On the other hand the reform has brought to an end the state monopoly on media licensing. Kuwait now has 15 daily newspapers and dozens of privately-owned television channels. to go further Organisation Popular blogger charged with blasphemycenter_img News News January 21, 2016 Find out more News RSF_en News September 5, 2014 Find out more KuwaitMiddle East – North Africa Courts uphold newspaper’s closure, increase blogger’s jail termlast_img read more

‘We Expected Something Better’, SC On Prashant Bhushan’s Statement; AG Urges Court To Take ‘Compassionate View’

first_imgTop Stories’We Expected Something Better’, SC On Prashant Bhushan’s Statement; AG Urges Court To Take ‘Compassionate View’ LIVELAW NEWS NETWORK25 Aug 2020 1:04 AMShare This – xThe Supreme Court has adjourned its hearing in the Prashant Bhushan contempt case for thirty minutes after asking Bhushan and his counsel, Senior Advocate Rajeev Dhavan, to ‘think over’.At the beginning, Justice Mishra asked the Attorney-General for India, K K Venugopal, about what could be done and asked the AG to guide the Court. To this, the AG responded, “We have serious statements made…Your free access to Live Law has expiredTo read the article, get a premium account.Your Subscription Supports Independent JournalismSubscription starts from ₹ 599+GST (For 6 Months)View PlansPremium account gives you:Unlimited access to Live Law Archives, Weekly/Monthly Digest, Exclusive Notifications, Comments.Reading experience of Ad Free Version, Petition Copies, Judgement/Order Copies.Subscribe NowAlready a subscriber?LoginThe Supreme Court has adjourned its hearing in the Prashant Bhushan contempt case for thirty minutes after asking Bhushan and his counsel, Senior Advocate Rajeev Dhavan, to ‘think over’.At the beginning, Justice Mishra asked the Attorney-General for India, K K Venugopal, about what could be done and asked the AG to guide the Court. To this, the AG responded, “We have serious statements made by former Judges about Supreme Court having failed democracy. I also have a complete list of former SC Judges making comments about corruption in judiciary.”The AG then continued :”They seek the improvement of administration of justice. This is a case where your Lordships should forgive him (Bhushan) or perhaps warn him. It is not necessary to punish him.” Justice Mishra, with reference to the Supplementary Statement submitted by Bhushan, stated, “We expected something better than this. What can be done if he thinks he has done no wrong.” The AG, at this juncture, referred to a contempt case against Bhushan for his remarks about the AG’s submissions in the CBI Director case was withdrawn after he expressed regret. Accordingly, the AG submitted to the Court that this was a case where the Court could take a “compassionate view” and that the same would be appreciated by the Bar and would befit the status of the Court. The AG further informed the Bench about the several PILs which had been filed by Bhushan for the benefit of people and that the Court should consider his public work. Justice Mishra responded, “What is the point of giving warnings to Bhushan if he himself has no inkling that he has done wrong. You yourself had filed contempt against him, which was withdrawn only after he expressed regret.” The AG suggested to the Court to take Bhushan’s remarks off-the-record and close the case. To this, Justice Mishra said, “How can they be taken off-the-record when Bhushan himself says they are his bonafide belief?” Justice Gavai too stated that 3 days had been given for expressing apology and Bhushan instead filed a Supplementary Statement. The AG then invoked the Arundhati Roy case wherein the Supreme Court had observed that “Our shoulders are broad enough to shrug off”. Accordingly, he suggested the Court to give one more chance to Bhushan to express regret. The Bench then perused the Reply Affidavit which had been filed by Bhushan. Justice Mishra observed, “Can those allegations be construed as defence?” The AG noted, “If there is an expression of regret, and if the Affidavit is withdrawn, perhaps the case can be dropped?” To this, Justice Mishra stated, “How can the Affidavit be withdrawn when they insist that it should be considered?” Justice Mishra noted that a person may have different opinions about a judgement, but the blame could not be attributed to the Judges. The AG responded that Bhushan had not hesitated to state that he also had the greatest of respect for the Court. “In 2009 case, he has expressed regret. Likewise, if he expresses regret in this, that should be the end of this unfortunate case”. Justice Mishra : Your advise is welcome. But he should withdraw his allegations.AG : Yes, he should withdraw his allegations too.#PrashantBhushan #[email protected] #SupremeCourt— Live Law (@LiveLawIndia) August 25, 2020While Justice Mishra welcomed the AG’s advice, he remarked that the allegations should be withdrawn. The AG concurred with this, and noted that he could not submit anything further than this as it was for Dhavan and his client (Bhushan) to submit what they wanted. Accordingly, the Court allowed 30 minutes of time to Dhavan and Bhushan to “think over” the matter and come back with their submissions. Live Updates from the hearing may be read here Update at 3:26 PM – SC reserves judgment on sentence. Report of the hearing during the afternoon session may be read here :’Tells Us What Is Wrong In Using The Word “Apology”‘: Asks Justice Mishra As SC Reserves Judgment In Prashant Bhushan Contempt Case Over Two Tweets Next Storylast_img read more

Almost €30 million being invested in local and regional roads

first_imgAudioHomepage BannerNews Previous articleLocal school to get ‘vital’ extensionNext articleUnion recognition should be a precondition for Udaras funding – Pringle News Highland WhatsApp Almost €30 million has been allocated to Donegal County Council for the local and regional roads network in Donegal, with a number of bridges also included in the programme.Minister Joe Mc Hugh said this afternoon the projects being funded include further works on Cockhill Bridge, and more funding also included for Fintra Bridge and the Tyrconnell Bridge in Donegal Town. Nine other bridges are also being improved.Funding is also included for the Laghey-Pettigo Road and the Swilly Road and Letterkenny Southern Ring Road.Minister Mc Hugh says this is combined with the €34 million already announced for the county’s national road infrastructure. He says this will lead to shorter journey times, safer roads and quality roads that locals and visitors alike will want to use.Work is also continuing on a number of key projects, including the N56 around Mountcharles and the Gweebarra bends and work on the Blue Banks near Letterkenny.However, Leas Ceann Comhairle and Donegal Deputy Pat The Cope Gallagher says the allocation is down on last year……..Audio Player Up/Down Arrow keys to increase or decrease volume. Pinterest Derry draw with Pats: Higgins & Thomson Reaction FT Report: Derry City 2 St Pats 2 Important message for people attending LUH’s INR clinic By News Highland – February 1, 2019 FULL LIST OF GRANTS Pinterest News, Sport and Obituaries on Monday May 24th Facebook RELATED ARTICLESMORE FROM AUTHOR WhatsApp Google+ DL Debate – 24/05/21 Google+ Facebook Almost €30 million being invested in local and regional roads Twitter Twitter Arranmore progress and potential flagged as population growslast_img read more

Energia funding applications now open in Donegal

first_img Twitter By News Highland – October 26, 2019 WhatsApp Loganair’s new Derry – Liverpool air service takes off from CODA Pinterest Facebook Twitter Energia funding applications are now open for community and charitable organisations in Donegal.The energy provider is calling on organisations located within 7.5km radius of the wind turbines at the Meenadreen Extension Wind Farm to apply for funding under the Energia Meenadreen Community Benefit Fund.Eoghan Murphy has more:Audio Player Up/Down Arrow keys to increase or decrease volume. Google+ Previous articleDerry’s hat-trick hero Junior speaks of his delightNext articleMigrants in Donegal urged to seek advice on rights and entitlements News Highland WhatsApp Google+center_img Pinterest News, Sport and Obituaries on Monday May 24th AudioHomepage BannerNews Arranmore progress and potential flagged as population grows DL Debate – 24/05/21 Important message for people attending LUH’s INR clinic Energia funding applications now open in Donegal Facebook Nine til Noon Show – Listen back to Monday’s Programme RELATED ARTICLESMORE FROM AUTHORlast_img read more

Two lost dogs reunited with family for Christmas thanks to bus driver

first_imgMilwaukee County Transit System(MILWAUKEE) — It’s a Christmas miracle for two dogs in Milwaukee, and they have a bus driver to thank. When a pit bull and Doberman pinscher were seen running in and out of the street last week after somehow getting out of their family’s yard 2 1/2 miles away from home, a bus driver spotted the pair on the road and sprung into action. Jamie Grabowski, a bus driver for the Milwaukee County Transit System (MCTS) and an avid animal lover, spotted the two pups alone on the street around midnight as she was wrapping up her bus route.Concerned about the pair either freezing in the cold or getting hit by a car, she stopped her bus, opened the driver’s side window and called out to them.On the bus surveillance camera, Grabowski heard saying to the dogs, “You need to go home right now … come on, come on inside!” The footage then shows Grabowski opening the door and helping guide the pair onto her bus before contacting MCTS dispatchers to notify them about the four-legged friends.Grabowski sat and played with the dogs until a police officer arrived. He ended up transporting them to the Milwaukee Area Domestic Animal Control Commission (MADACC) and they determined that the “very sweet and playful” pair were in good health. The dogs’ owners are praising Grabowski for her quick thinking and are grateful to have their pups back just in time for Christmas. Grabowski said she was happy that she was in the right place at the right time to help the dogs out.Copyright © 2019, ABC Audio. All rights reserved.last_img read more

Watch all the Clocks

first_imgThe passing of time has always been a fascinating and troubling notion for mankind, and the thought of somehow ‘caging the minute’, to borrow from MacNeice, is inspiration enough for the endeavors of clockmakers. Horological Masterworks , running now in the Museum of the History of Science, takes us through one of the peaks of English engineering, mapping the rise of the pendulum mechanism alongside the careers of several master clock makers. The exhibition passes under four distinct headings, beginning with Prologue – domestic clocks up to about 1660 – and ending with the proud title of Perfection – the pinnacle of seventeenth century clock making. The clocks also reflect British history, their production being greatly encouraged by the restoration of the monarchy in 1660, and the patronage of the Royal Society. Although rather specialised, this is definitely a thought-provoking exhibition: we are presented with examples of clocks ranging from the more basic to the most elaborate: rugged looking ‘lantern clocks’– dented boxes of wheels and cogs held together by springs and brass rods, under the umbrella-like dome of the bell. Further on, both undersized and ostentatious grandfather clocks surround the visitor, with their etched brass faces. As the exhibition nears its end, the clocks become more elaborate, with architectural columns and gleaming silver mounts. Mirrors permit the visitor to view the insides of several clocks, and wonder at the regular rotations of tiny weights and axles. With its detail – running through the list of ‘great’ clock makers, from Fromanteel to Tompion – and several samey examples of each kind clock, this is not a general interest exhibition. And let’s be honest, clocks are just not going to be exciting until you’ve left Oxford behind and are considering soft furnishings and colour schemes. Students might also be put off the numbers of older visitors whose conversations seem to revolve around comparing their grandfather clocks to those of the exhibition, and speculating values. However, these are remarkable examples of ingenuity as well as artistry. Despite the initial clock’s warning that on this moment several samey examples of each kind clock, this is not a general interest exhibition. And let’s be honest, clocks are just not going to be exciting until you’ve left Oxford behind and are considering soft furnishings and colour schemes. Students might also be put off the numbers of older visitors whose conversations seem to revolve around comparing their grandfather clocks to those of the exhibition, and speculating values. However, these are remarkable examples of ingenuity as well as artistry.ARCHIVE: 3rd Week TT 2003last_img read more

Ocean City’s Black Friday Delivers Old-Fashioned Holiday Experience

first_imgCarolers from Fox Vocal Arts add to the festive charm during Ocean City’s downtown Black Friday celebration. By Maddy VitaleAlayna and Nick Pagano, of Lafayette, Pa., walked with their children, Maci and Dominick, along Asbury Avenue in Ocean City on a brisk, but sunny Black Friday.As they strolled down the avenue holding hands, the family stopped to look at merchandise outside of the downtown shops, as a horse and carriage rode by.“We came last year and thought we had to do this again,” Alayna Pagano said. “We like the small-town feel. This has become our tradition.”Nick Pagano noted that the family has had a second home in Ocean City for a decade.Ocean City gives the family an alternative place to buy holiday gifts while enjoying the old-fashioned charm of the city on one of the busiest shopping days of the year, Nick Pagano noted.“It is such a magical experience after Thanksgiving,” he said. “And the kids had a really good time last year.”Alayna and Nick Pagano with their children, Dominick, 4, and Maci, 6, make shopping in downtown Ocean City their holiday tradition.The Paganos’ 6-year-old daughter, Maci, enjoyed Santa Claus last year and hoped to get her photo taken with him again this year.Dominick, 4, liked the carriage ride.This year, the Paganos said they would stick to the same game plan as last year during the shopping event that goes from Sixth Street to 11th Street.They planned to browse a couple of stores, pick up some gifts, take a horse and carriage ride and get their photos with Santa at Mark Soifer Park, across from City Hall.“We will grab lunch in between,” Alayna Pagano said with a laugh.The relaxed downtown shopping experience is in contrast to the hustle and bustle of the malls or big-box stores.City Hall is decked out in all its holiday splendor.Fake snow filled the air, coming from a machine at City Hall. A stilt-walker entertained crowds waiting in line for carriage rides.Carolers wearing Victorian-style clothing strolled down Asbury Avenue, stopping on corners to sing favorite holiday classics.Wreaths with big red bows and garland wrapped around lampposts completed the festive atmosphere for the aptly named “Our Miracle on Asbury Avenue, an Old-Fashioned Family Christmas.”Holiday tunes added to the festivities, just loud enough to be background music for shoppers who filled the streets and stores.Stefanie Henwood, of Philadelphia, looks at ornaments in Mia’s Christmas Gallery at 755 Asbury Ave.Ocean City Regional Chamber of Commerce Executive Director Michele Gillian said the event began in 2008.“It went from a few hundred people to a few thousand,” Gillian said of the growth over the decade. “It is really a great economic energizer for the downtown. It is a community event.”Gillian said many year-round residents enjoy the shopping extravaganza. She added that many of the customers, like the Paganos, are second homeowners in Ocean City.“There are 14,000 second homeowners in Ocean City. That is the biggest number in New Jersey,” she pointed out.Gillian said there are many reasons why people love coming to Ocean City to do their holiday shopping.The old-fashioned feel and quaintness, to photos with Santa in a lifeboat, add to the city’s unique and special qualities.Ilana Bohm, of East Brunswick, and her daughter, Avital, 9, browse shops along Asbury Avenue.As Gillian spoke, a little girl slipped a letter into a red mailbox with the words “Santa’s Mailbox” painted on it.“We answer all of the letters,” Gillian said with a smile as she looked out along the avenue at Mark Soifer Park where shoppers lined the sidewalks.“It is great to see this grow. It really is a magical holiday weekend,” she said. “Ocean City is all about tradition.”And the festivities have just begun. Throughout the weeks leading up to Christmas and First Night, there are events, shopping specials, entertainment, photos and breakfast with Santa and a host of other activities to keep the shore town hopping when the temperatures drop.Families line up for carriage rides. Brian and Colleen Horcher, of Philadelphia, wait with their son, Liam, 6, and 4-year-old daughter, Adalyn.Brian and Colleen Horcher, and their children Liam, 6, and Adalyn, 4, along with their grandmother, Beth Anne Hampson, all of Philadelphia, waited in line for a carriage ride.The family already saw Santa Claus and had bags from a shopping spree. Now it was time to enjoy the ride.“It will be exciting,” said Liam.The Horchers said they enjoy the holidays in Ocean City.“We vacation down here every summer,” Colleen Horcher said.People whizzed in and out of shops. Mia’s Christmas Gallery manager Carol Phillips said business was exceptional.“It is super busy. We have been busy since “Earlier Than the Bird” last week,” Phillips said of the city’s kick-off event to begin the holiday shopping season. “We try to carry things that you just can’t get at big-box stores.”Ocean City Special Events Coordinator Michael Hartman with Junior Miss Ocean City Julia Wilson (white scarf) and other members of the Ocean City Theater Company, take a break from practicing for a performance later on in the day on City Hall’s steps.Later in the evening, beginning at 5 p.m., the crowds were wowed by Santa’s arrival on the roof of City Hall and special guest, singer Jackie Evancho. Mayor Jay Gillian, members of City Council and other dignitaries were also in attendance.Ocean City’s Special Events Coordinator Michael Hartman, who emceed the night festivities, said, “Christmas in the downtown is an amazing way to kick off the holiday season. It is a full-on, grand scale, festive event, featuring talent from within and outside of the community.”The sales and festivities continue through the holidays. On Saturday, the Chamber hosts “Small Business Saturday,” which will feature shopping specials all day in the downtown along Asbury Avenue from 6th Street to 14th Street.For information about the Ocean City Regional Chamber of Commerce call (609) 399-1412, visit or download the new Ocean City Vacation mobile app on your smart phone. Santa appears on the roof of City Hall. (Courtesy Ocean City Chamber of Commerce)From left, Special Events Coordinator Michael Hartman and Director of Community Services Michael Allegretto with singer Jackie Evancho, who receives a warm welcome from Mayor Jay Gillian and other city dignitaries. (Courtesy Ocean City Chamber of Commerce)last_img read more

Insight into seeing

first_imgIt’s a question that seems to offer tantalizing hope to those suffering from vision impairment. Why is it that when the optic nerve is damaged — either through trauma or disease — few of its neurons survive and fewer still regenerate? Most wither and die.A new study conducted by Harvard scientists could point to the answer.The study, led by Joshua Sanes, the Jeff C. Tarr Professor of Molecular and Cellular Biology and director of the Center for Brain Science, and Zhigang He, professor of neurology at Boston Children’s Hospital, is the first to allow researchers to look at neurons that survive and those that don’t side by side, in an effort to understand what surviving neurons are doing that others aren’t. The study is described in a March 18 paper in the journal Neuron.“The ability to directly compare successes and failures in the very same animal … that’s going to be a big help in understanding the differences between these cells,” Sanes said. “These cells are remarkably similar to each other, and yet one type survives and the other types either die or survive but don’t regenerate.”The study grew out of a combination of the two central questions pursued by Sanes’ lab and He’s lab.“We are interested in how the retina gets wired up during development,” Sanes explained. “There are about 100 different cell types in the retina, and during development they all sort out to form these very complicated circuits.”Zhigang He. Courtesy of Zhigang He Using a variety of techniques, including green fluorescent protein, Sanes and colleagues have been able to identify and trace the paths of neural circuits in the retina that connect light-sensing photoreceptors to image-processing retinal ganglion cells.With axons that stretch through the optic nerve to the rest of the brain, retinal ganglion cells play a critical role in visual processing. Scientists believe there are some 30 types of retinal ganglion cells, each of which performs a specific function — for example, some fire when objects are moving upwards, while others recognize movement in any direction — to preprocess visual information before it reaches the brain.Meanwhile, He and colleagues had long been using the optic nerve as a model for devising interventions that could coax more neurons to regenerate following an injury.“If you cut a nerve in the periphery, such as a nerve to a muscle, the axons regenerate quite well and restore function,” Sanes said. “But if you cut axons in the brain or spinal cord, they do not. The same is true if you cut the optic nerve. There’s very little regeneration. A number of people have tried to study what’s going wrong, and whether we can cause those cells to regenerate, with some limited success.”The two teams began collaborating, Sanes said, with the goal of understanding whether, when the optic nerve is cut, neurons die off uniformly, or whether certain types of cells are more likely to survive.“The reason this would be important to know is because if it were the latter, then we would have a great way to compare those that survive with those that don’t,” he said. “And, in fact, what we found is that different types of cells die at very, very different levels. There were a few types in which we saw none surviving, and others in which 80 percent of the cells survived.”The Sanes and He labs found that among the most likely survivors are what are known as “alpha” cells. Though they initially make up just 5 percent of neurons in the optic nerve, they make up 20 percent of the neurons that survive after the optic nerve is cut. The researchers went on to show that alpha cells are the ones that react most strongly to efforts to promote regeneration of axons through the optic nerve. Regeneration will be necessary to reconnect the eye to the brain following injury.Sanes and He then found clues that may point to the hardiness of alpha cells and their ability to regenerate. “One thing we found was [that] they contain a protein called osteopontin that acts like a growth factor,” Sane said. “It’s not enough to make them regenerate, or else they’d regenerate without extra help, but we found that if we added osteopontin back into the retina in larger amounts, it would promote regeneration of these cells.”The researchers also administered a second growth factor, called IGF-1, to help spur regeneration of the neurons, Sanes said. Tests later revealed that alpha cells contain receptors for the growth factor, which sets off a signaling cascade in the neurons.Though there are still outstanding questions about why alpha cells survive where others don’t and whether other cell types can be encouraged to regenerate, Sanes expressed cautious optimism that making side-by-side comparisons could one day lead to advances in restoring damage to the optic nerve.“There is a lot to be learned about how to get other cell types to be competent to regenerate,” he said. “The good news is we know how to purify these types of cells, and other types of retinal ganglion cells, and compare them. This is a glimmer of hope, but there have been other glimmers in the past that didn’t succeed, so I think we need to be cautious.”last_img read more